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Please skip it or consult your healthcare provider first if you: Have a copper metabolism disorder (such as Wilsons disease or copper toxicity) or severe liver disease that affects copper processing

However, in some circumstances they can be beneficial

Kaede is a photoconvertible protein, which permanently changes its fluorescence emission from green (518 nm) to red (582 nm) upon photoactivation with near-UV light

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This matches the clinical trial inclusion criteria, which recruited obese subjects