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reported that the selective blockade of respiratory chain complex I by MPP + induces dopaminergic neuronal degeneration and PD symptoms, suggesting that defects in the respiratory chain play a role in the pathogenesis of PD [82]

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Remaining amino acids were measured by mixing 10 L of the aqueous extract with 90 L 13 C- and 15 N-labeled amino acid standard solution (10 g per mL) and analyzed using an Agilent 1260 HPLC coupled to an API6500 tandem mass spectrometer

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