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In 1966 the US Government introduced a health warning that appeared on every packet sold in the USA: 'Caution: Cigarette Smoking May be Hazardous to Your Health.' The government strengthened this warning in 1969 to: 'Warning: The Surgeon General Has Determined That Cigarette Smoking is Dangerous to Your Health'

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The study also showed that although the heritability of lung function and COPD was estimated to be between 38 and 50%, individual genetic variants only account for a small fraction of the overall risk associated with COPD [50]