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B lymphocytes are sparse and CD1+ Langerhans cells are diminished in the epidermis but increased in dermal papillae

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Protection of human pancreatic islets from lipotoxicity by modulation of the translocon

10 Summary and outlook Tophus formation is a progressive and dynamic pathological process that begins with hyperuricemia as its fundamental basis and is driven forward by alterations in the local microenvironment