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Among sPLA2 phospholipases, the dominant isoform in keratinocytes, both human (human primary epidermal keratinocytesHPEK) and mouse (murine primary epidermal keratinocytesMPEK), is the sPLA2-IIF isoform

MP also activates the STAT6-STAT3 signaling pathway, inducing the expression of the mucins MUC5AC and MUC5B, thereby downregulating FOXA2, leading to excessive airway mucus secretion, which exacerbates airway infections and is a major cause of mucus obstruction in various chronic airway diseases (132)

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4.3%) and anemia (5.6% vs

Molecules 29, 2738