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Healthy individuals who desire an energy boost or to increase metabolism and balance mood Patients with Celiac disease, Crohns disease or following weight loss surgery Those following a vegan or vegetarian diet Patients with Pernicious anemia Patients with Psoriasis Patients with immune disorders, such as Graves disease or Lupus Patients over 50 years of age the absorption of vitamin B-12 decreases

Systemic hypertension, diabetes mellitus, atherosclerosis, and smoking are reported to be more common in patients with RVO.1,2,10 Sclerosis of the retinal artery which is associated with these systemic disorders may result in further compression of the vein, when the increased rigidity of arterial wall and contraction of the adventitial sheath shared by artery and vein occur

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Huang Y, Chen X, Dikov MM, Novitskiy SV, Mosse CA, Yang L, et al