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Direct Adrenergic Agonism: Ephedrine is also able to directly bind to multiple post-synaptic adrenergic receptor subtypes to initiate intracellular signaling cascades: : Activation of vascular smooth muscle 1 -Adrenergic Activation 1 -adrenergic receptors produces arterial and venous vasoconstriction, leading to an increase in systemic vascular resistance (SVR), diastolic blood pressure, and systolic blood pressure (Solanki et al, 2014)

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Clinical studies have confirmed that AOD-9604 shows no adverse effect on insulin sensitivity when assessed using glucose clamp techniques, unlike full-length growth hormone which can impair glucose metabolism

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