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Cell culture, oxidative stress, and antioxidants: avoiding pitfalls

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7.2.5 Potential for drug modification The dimers of artemisinin and the development of hybrid drugs have shown significant potential

The authors conclude that this antioxidant-based support is well tolerated and may provide clinically meaningful benefits, although controlled trials are needed to confirm efficacy ( Weight of evidence: Overall evidence is Low : primarily preclinical with heterogeneous designs and no consistent human biomarkers

Tranquilli AL, Bezzeccheri V, Giannubilo SR, Scagnoli C, Mazzanti L, Garzetti GG