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References 1 AksoyS.SzumlanskiC

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes (ACHIEVE-1)

In disease models, animal studies suggest neuroprotective effects in conditions such as Alzheimers and Parkinsons disease

5-Amino-1-methylquinolinium iodide is the lead first-in-class small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme overexpressed in white adipose tissue of obese individuals where it consumes the methyl-donor pool and depletes tissue NAD