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Oral changes Vitamin B12 deficiency causes swollen gums and sore tongue

When liver function deteriorates significantly, the combination of released stored B12, increased circulating haptocorrin, and reduced hepatic clearance can result in markedly elevated total serum B12 levels

by Chris Kresser [ Wu Y, Kajdacsy-Balla A, Strawn E, Basir Z, Halverson G, Jailwala P, Wang Y, Wang X, Ghosh S, Guo SW

In mouse models, copper deficiency impairs cardiac function, manifesting as reduced diastolic and systolic performance alongside a diminished inotropic response to beta-adrenergic stimulation, which compromises the heart's ability to adapt to stress [206]

TG13 miscellaneous etiology of cholangitis and cholecystitis