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The gluthathione can also modify the eumelanin (dark pigment) into pheomelanin (light pigment)

Foxp3 mRNA expression was also induced, consistent with the acquisition of Treg suppressive function [159]

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As such, ketamine has demonstrated rapid antidepressant efficacy in refractory BD, with a concomitant neuroprotective shift in kynurenine metabolites [119]