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Moreover, a relatively small sample size of the subgroup of patients with severe vasculogenic ED might have prevented to capture slightly significant improvements in PSV at dynamic PDU upon l-ARG supplementation, particularly in patients with borderline scores indicating severity, therefore making it challenging to provide conclusive information concerning the potential effect of l-ARG supplementation in patients with borderline severe vasculogenic ED

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Ruiz, C

The heterogeneity in this study was substantial, and we speculate that most of the heterogeneity may have come from clinical sources

These effects were also associated with significant reductions in measures of oxidative stress, including decreased lipid peroxidation and increased total reduced glutathione level