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Methods: Detail clinical history and examination was performed and whole exome sequencing with repeat expansional disorder genetic assays were done

FASN emerged as the top candidate, with 10 cysteine sites showing increased oxidation levels, far exceeding other proteins, which had at most 2 sites (Figure 5G)

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The combination of 5-FU with IKE increased the level of ROS compared to the administration of drugs alone (Fig