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Very few studies explored the effect of antioxidants on semen quality of men with genitourinary inflammation (n=3), a hyperinsulinemic state (n=1) and recurrent pregnancy loss in female partners (n=1) (Table 2), and are hence insufficient for evidence-based recommendations for their use

XL contributed to formal analysis and writing-review and editing

Their chemical structures, receptor targets, and clinical uses differ significantly

In the uterus, oxygen concentration is just about 35%

First, most studies included small sample sizes predominantly composed of healthy young female participants, which limits statistical power and reduces the generalizability of results to clinical populations