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Materials and methods Animal models In these studies, APOE-TR mice were housed in groups of up to four under standard laboratory conditions at 23 1C, 50 5% humidity, with a 12-h light/dark cycle and access to food and water ad libitum

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Wang W., Pan D., Liu Q., Chen X., Wang S

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Butyrate enhances the efficacy of chemotherapeutic agents via two mechanisms: it inhibits tumor cell glycolysis (the Warburg effect), reducing energy supply and sensitizing cells to chemotherapy, and it activates the GPR109aAKT pathway, inducing cell cycle arrest and apoptosis, thereby increasing chemosensitivity (Geng et al., 2021)