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Melatonin administration to aged mice also demonstrated the therapeutic utility of this compound in the treatment of age-related cardiac sarcopenia, since it preserved the normal cardiomyocyte structure and restored their number, as well as to reducing -myosin heavy chain expression (a marker of cardiac hypertrophy) in these animals

Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, Tall AR

In some architectures, the IdP and RP do not communicate directly with each other

However, the differences in methodologies and experimental design prevent direct comparison between these studies

Lymphocyte DNA damage in rats challenged with a single bout of strenuous exercise