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Melatonin binds to two membrane-related G protein-coupled receptors (GPCRs) called MT1 and MT2 [155, 156]

And you can actually show how this hierarchy is constructed

10.1016/j.neuroimage.2010.08.078 Summary Keywords neurofeedback, protocol tutorial, EEG, frequency band modulation, fm-theta, cognitive enhancement Citation Enriquez-Geppert S, Huster RJ and Herrmann CS (2017) EEG-Neurofeedback as a Tool to Modulate Cognition and Behavior: A Review Tutorial