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EHA (2018) S850

435 Gain of function of sodium channels leads to increased neuronal excitability, signal transduction, and neurotransmitter release

In this cycle, vitamin B 12 is a necessary cofactor for methionine synthase, an enzyme involved in the methylation of homocysteine to methionine

Jari Laukkanens lab at the University of Eastern Finland

Elevated B12 Symptoms: Signs of Too Much Vitamin B12 While rare, excessive B12 intake can lead to certain symptoms: Acne or rosacea Headaches Nausea and vomiting Diarrhea Fatigue Tingling in hands and feet It's crucial to note that these symptoms can also be caused by other conditions, so always consult a healthcare professional for proper diagnosis