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Female gender was associated with a more severe reaction, while higher serum acetaminophen concentrations were associated with less severe reactions

40 In terms of immunity, amino acids are involved in immune cell proliferation, differentiation and functional activation

As these studies implicated disulfiram as a potential antileukemia drug, we therefore undertook full doseresponse resazurin reduction-based viability assays to thoroughly characterize the effects of the drug in a larger and more diverse panel of cells comprised of acute leukemia cell lines ( n = 16), solid cancer cell lines ( n = 7), and non-malignant cells ( n = 2)

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Intriguingly, a Western diet high in PUFAs can induce intestinal inflammation in mice lacking one allele of GPX4 in IECs, which implies that dietary PUFAs may be a trigger of GPX4-restricted mucosal inflammation phenocopying aspects of human CD (143)