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These mechanisms are intricately linked and together lead to changes in kidney structure and function

Clonality Monoclonal Clone Number OTI1B8 Isotype IgG1 Immunogen Full length human recombinant protein of human GSS (NP_000169) produced in HEK293T cell

Mice were maintained at the animal facility of CHU Sainte-Justine Research Center in accordance with the protocol approved by the Institutional Animal Care and Use Committee ( Comit institutionnel des bonnes pratiques animales en recherche , CIBPAR#527)

It can reverse cortisone-induced inhibition of wound healing and restore normal tissue repair signaling without triggering rebound inflammation

Furthermore, even with increasing concentrations, Psa-AR maintained minimal off-target effects on AR degradation, collectively demonstrating its superior target specificity through ligand-directed precision (Fig