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tetracyclines e.g., apicycline, chlortetracycline, clomocycline, etc

Li H, Dun Y, Zhang W, You B, Liu Y, Fu S, et al

Glutamatergic neurotransmission has already been adopted as a promising target for neuro disorder drug development

Shaking the vial can physically break these chains apart (a process called shearing), destroying the molecules structure and rendering it ineffective for research