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Diabetes 67 , 17011709 (2018)

On the other hand, compensatory angiogenesis serves as an adaptive response to tissue hypoxia, a hallmark of the aging brain

Pathways for small molecule delivery to the central nervous system across the bloodbrain barrier

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Low levels of reduced glutathione (GSH) in erythrocytes (Ikawa et al., 2015) of patients with ALS, a systemic pro-inflammatory state (increased levels of IL-6 and IL-8) and an impaired antioxidant system (Ehrhart et al., 2015) have been highlighted