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Iron overload is a key negative regulator of leptin and adiponectin

Lancet 321:13751376 Waring WS, Stephen AF, Malkowska AM, Robinson ODG (2008) Acute ethanol coingestion confers a lower risk of hepatotoxicity after deliberate acetaminophen overdose

Our meta-analysis was registered in PROSPERO under the identification number CRD42023418467

Specifically, bioactive molecules such as leukotrienes and prostaglandins produced during AA metabolism via LOX and COX can directly or indirectly increase NOX complex activity, leading to the catalysis of intracellular ROS synthesis, including O , thereby participating in the regulation of oxidative stress and cell signalling pathways [15]

Knockdown of MITD1 significantly decreased cell proliferation and migration and triggered ferroptosis through the TAZ/SLC7A11 pathway in ccRCC cells [294]