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Description

BRD4 negatively regulates ferroptosis by activating xCT, repairing the DNA, and inducing senescence-associated secretory phenotype (SASP), a ferroptosis resistant cellular program (Tasdemir et al., 2016

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The April 2025 FDA safety alert on compounded topical finasteride is the most important recent development

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The C-CRD of Yap1 consists of a leucine-rich export signal (NES) and two cysteine-rich domains (CRD) positioned at the N- and C-termini

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As mentioned previously, the lactylation of RIG-I at K852 promotes liver metastasis in CRC

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Cell (2016) 167:829842.e13.10.1016/j.cell.2016.09.031 35 MurphyMP

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