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The full-length TrkB isoform is a typical tyrosine kinase wherein homodimerization during ligand binding causes intracellular cross-tyrosine phosphorylations (30)

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Researchers value it for its: Complex peptide structure Novel molecular interactions Potential for advanced laboratory exploration Use in controlled scientific environments It is important to note that Dihexa is strictly for research purposes only and is not approved for human use

The need for these mimetics arises from a fundamental pharmacological challenge: BDNF itself is a terrible drug candidate