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SKU: 18152184603
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Similar content being viewed by others Introduction Proteins carry out and assure the maintenance of almost all cellular functions, lending support to a paradigm arguing that aging and age-related diseases (ARDs) are complex consequences of the cumulative oxidative damage to proteins 1,2

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Cu deposition in renal tissues induces oxidative stress through downregulation of anti-apoptotic genes [B-cell lymphoma-2 genes (BCL2)], upregulation of pro-apoptotic genes (BCL2-antagonist/killer 1, BCL-2-associated X protein), and increased expression of apoptosis proteins (Caspase-9, Caspase-3) (124)