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Patients should be monitored for signs of infection or unusual bruising

Cysteine oxidation promotes a post-translational modification of the GR that impairs its nuclear expression and binding to the glucocorticoid consensus and modifies the GR protein by decreasing available sulfhydryl groups and decreasing nuclear GR expression and activity [20]

Under serine deprivation, ATF4 is induced and activates the transcription of SSP-related genes

JAD was funded by a Cancer Research UK Biotherapeutic Project grant to ALP (C52915/A23946)

Melanin is produced by specialized cells called melanocytes, and its overproduction can lead to hyperpigmentation and uneven skin tone