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Collectively, a decade of incremental advances positions AD-MSCs as dual-purpose agents: they can be bio-engineered into smart living missiles that deliver cytotoxic payloads with spatiotemporal precision against metastatic ovarian cancer, and, when used in their nave or minimally modified forms, can rejuvenate the chemotherapy-damaged ovary, restore endocrine balance and prolong fertilitylaying the groundwork for personalised, fertility-sparing cancer care