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It has been reported that epithelial-specific deletion of the focal adhesion kinase (FAK), which is necessary for cell migration, leads to epithelial cell apoptosis and enhanced bleomycin injury, while enhancement of the Notch signaling pathway leads to functional impairment of Tp63-expressing stem cells in the bronchiolar epithelium

Nat Rev Clin Oncol (2012) 9(12):68899

Finally, studying allelic variants in genes involved in folate metabolism are useful and relevant not only for the nutrigenetics field but also for pharmacogenetics

Disulfide bond disruptors are a class of agents being investigated for potential anticancer effects (Wang 2019)

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