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Given that Cu accumulation occurs in a variety of diseases and conditions, including Wilsons disease, certain neurodegenerative diseases, and cancer, it is reasonable to speculate that cuproptosis may play a pathogenic role in these diseases and may therefore serve as a potential therapeutic target

mutans tlp-C41A mutant in a rat model of dental caries produced less severe carious lesions on all molar surfaces, indicating that glutathionylation of Tlp has a role in virulence [42]

A related study found that LND and BPTES were able to induce glycolysis and inhibit glutamine metabolism, which was accompanied by significant mitochondrial damage, ultimately blocking energy supply and posing a threat to tumour survival, to efficiently kill tumours

Available at: www.sciencedaily.com/releases/2009/10/091009092344.htm

Reads with an average quality 2 mismatches in the bases for the remaining part of the primer were removed, and this resulted in a total of 3,332,352 tags, averaging 133,294 tags/sample with an average length of 481 bp