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29,37 Norrin protein can also bind to Frizzled class receptor 4 (FZD4) and LRP5/6 to form a ternary complex and promote the downstream signal transmission of Wnt/-catenin

This Review describes the mechanisms of action of antioxidants synthesized in vivo, antioxidants derived from the human diet and synthetic antioxidants developed as therapeutic agents, with a focus on the gaps in our current knowledge and the approaches needed to close them

In the absence of mutations in DNA repair-coding genes, FA can also underly a variant of a human inherited bone marrow failure syndrome (IBMFS) caused by mutations in both ALDH2 and ADH5 10, 14

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Animals 11(6):1494 Jing Y, Liu H, Xu W, Yang Q (2017) Amelioration of the DSS-induced colitis in mice by pretreatment with 4, 4-diaponeurosporene-producing Bacillus subtilis