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3.3 Pathological markers: axonal degeneration, demyelination, and microvascular damage Current studies consistently indicate that the core pathological manifestations of DPN include: axonal degeneration (Galiero et al., 2023), Schwann cell-mediated demyelination (Chong and Souayah, 2025), and neurovascular microcirculation dysfunction (Zhu et al., 2024), which together constitute the major forms of damage

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You have no way of knowing whether the product is sterile, whether it contains the correct peptide sequence, or whether it has been stored and shipped under appropriate conditions to maintain its integrity

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