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Therapeutic neovascularization involves interventions that upregulate cytokines or receptors to promote new blood vessel growth in the ischemic myocardium

de Joode AA, Sanders JS, Puchal X, Guillevin LP, Hiemstra TF, Flossmann O, Rasmussen N, Westman K, Jayne DR, Stegeman CA (2017) Long term azathioprine maintenance therapy in ANCA-associated vasculitis: combined results of long-term follow-up data

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3), can transport glutamine into tumor cells to drive metabolic processes such as the TCA cycle and REDOX balance, and the upregulated SLCs in cancer cells also increase the glutamine supply to tumor cells [36]