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& Houk, K

For example, the E3 ubiquitin ligase NEDD4L promotes ferroptosis in ESCC by facilitating xCT ubiquitination, thereby inhibiting tumor cell growth and metastasis (Song J

mTOR signaling is dysregulated in cancer cells, while T cell function requires upregulation of mTOR ( 5.2 Targeting arginine, glutamine and the BCAAs for cancer therapy Because arginine, glutamine and the BCAAs are required for growth of cancer and immune cells, targeted deprivation or supplementation of these amino acids may lead to undesirable therapeutic effects ( + T cells

doi: 10.1515/BC.2004.072

Circ-STC2 promotes the ferroptosis of nucleus pulposus cells via targeting miR-486-3p/TFR2 axis