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We observed a significant increase in the autophagy substrate sequestosome 1 (SQSTM1, best known as p62) levels in both 6- and 20-week-old Alms1 -/- mice, as compared to age-matched WT controls, suggesting a reduction in autophagic flux (Fig

Most people notice significantly better function under load

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Curr Opin Invest 11:p298 Xiong Y, Peterson PL, Lee CP (1999) Effect of N-acetylcysteine on mitochondrial function following traumatic brain injury in rats