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One of these concerns the chemistry of the pigments present in the lenses of primates and certain other diurnal species

doi: 10.2174/1872213X12666180221161410 203 SalehiBAta AVAnil KumarNSharopovFRamrez-AlarcnKRuiz-OrtegaAet al

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Although OA pathogenesis is exceedingly complex, recent studies underscore the multifactorial nature of the disease, involving mechanical overload, inflammatory responses, metabolic abnormalities, and cell death ( Cartilage deterioration and subchondral bone remodeling are hallmarks of OA