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For example, kidney toxicity due to cisplatin occurs in about one-third of patients undergoing treatment (Wensing 2013)

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10.1007/978-1-4939-7831-1_1 206 MagyarK.HalmosiR.PalfiA.FeherG.CzopfL.FulopA.et al (2012)

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Ethanol-Induced Apoptotic Cascades and Their Role in Mood Regulation Chronic ethanol consumption has profound effects on the central nervous system, leading to significant alterations in neurotransmitter regulation that contribute to the development of depression