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Unlike recombinant GH therapy, sermorelin has not been strongly associated with severe fluid retention, insulin resistance, or joint pain in the short term, though long-term data are limited

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Additionally, DSIP attenuates ACTH and corticosterone release in response to stress, indicating an effect on the hypothalamic-pituitary-adrenal axis [8]

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Brain-derived neurotrophic factor delivered to the brain using poly (lactide-co-glycolide) nanoparticles improves neurological and cognitive outcome in mice with traumatic brain injury