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Corro N, Alarcn S, Astroza , Gonzlez-Stegmaier R, Aazco C

For example, HMOX1 is transcriptionally activated by IFI16, significantly decreasing radiation-induced lipid peroxidation, ROS generation, and intracellular Fe 2+ content, thereby suppressing ferroptosis and enhancing radioresistance ( STAT3 and STAT1 are two critical signaling molecules in the immune microenvironment of GBM that play significant roles in the regulation of ferroptosis

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120C149 (awarded to D.A.), Tbitak 2250 Grant (awarded to S.D.), NIH grant R35 GM149420 (awarded to J.J.H.) and Bulgarian National Science Foundation (BNSF) Grants KP-06-N91/3 (awarded to S.D) and KP-06-RILA/8 (awarded to A.G.)