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The side effects of gum fillers are mild and include swelling, bruising, and occasional hypersensitivity reactions

Subcutaneous injection is the gold standard because it delivers reliable systemic concentrations and allows for localized tissue targeting when needed

To potentially move them into Category 1 or final Bulks List status, the most effective approach is to present a persuasive case for their clinical efficacy and safety to the Pharmacy Compounding Advisory Committee (PCAC) and submit it to the FDA

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