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The mPOA represents a particularly important target, as this region integrates hormonal, sensory, and emotional inputs to regulate sexual behavior

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In contrast, RMS13 rhabdomyosarcoma cells that overexpress HRAS, KRAS, or NRAS are resistant to erastin and RAL3 (Schott et al., 2015), which means RAS does affect erastin sensitivity, while the oncogenic RAS pathway is not the sole determinant of ferroptosis sensitivity (Dixon and Stockwell, 2019)

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