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High levels of dopamine metabolism, iron, and calcium, coupled with mitochondrial dysfunction and neuroinflammation, contribute to the excessive production of ROS in the brains of PD patients (183)

Per BNF and BSH guidance: For confirmed deficiency without neurological involvement: 1 mg IM on alternate days for two weeks, then 1 mg every two to three months for maintenance

Protocol approach: frozen shoulder (adhesive capsulitis) Goal: Reduce capsular fibrosis, restore range of motion, manage pain Peptide approach: BPC-157: 300 to 500 mcg daily for anti-inflammatory and tissue healing properties TB-500: 500 to 750 mcg twice weekly for systemic anti-inflammatory and tissue remodeling Note on relaxin-2: While the most specifically targeted peptide for this condition, it remains largely in the research phase and is not widely available through standard channels Duration: Twelve to sixteen weeks (frozen shoulder has a prolonged natural course) Critical addition: Aggressive physical therapy within pain tolerance

doi: 10.3389/fnut.2023.1068343 Received 12 October 2022 Accepted 21 March 2023 Published 05 April 2023 Volume 10 - 2023 Edited by Andrew Scholey, Monash University, Australia Reviewed by Jessica Zuiga-Hernandez, University of Talca, Chile

Multiple ads contained the same spelling mistakes, stating they're part of a "Compommdding Pharmacy Alliance" or declaring that Ozempic's class of drug (GLP-1) "mimickers science"