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Epub 2022 Apr 20

Scand J Work Environ Health

For patients with PIH in Fitzpatrick types IV to VI, the combination of microneedling plus PDRN is often our preferred primary protocol because it avoids the laser risk in darker skin types while still producing strong clearance results

By applying NAPstars in combination with selective impairment of the glutathione and thioredoxin antioxidative pathways under acute oxidative challenge, we find an unexpected and conserved role for the glutathione system as the primary mediator of antioxidative electron flux

In vitro studies using ovarian cancer cell lines A2780 and SKOV3 reveal that SLT reduces cell viability by activating a ROS-mediated p53 pathway, resulting in G1 cell cycle arrest, enhanced apoptosis, and inhibition of cell migration and invasion