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This suggests that CaOx-exo exacerbates pre-existing renal injury caused by kidney stones, potentially through enhanced macrophage phagocytosis or upregulated expression of scavenger receptors, thereby increasing the uptake of exogenous exosomes [32]

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D., Manson, J

Homocysteine accumulates in the blood, causing vascular damage and micro-clotting, while downstream glutathione synthesis grinds to a halt

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