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doi: 10.1021/jm501506f 153 NairzM.SchrollA.HaschkaD.DichtlS.TymoszukP.DemetzE.et al

doi: 10.1016/j.freeradbiomed.2024.07.007 15 AkaikeTIdaTWeiFYNishidaMKumagaiYAlamMMet al

Further, a neurotransmitter deficiency state including the elevation of GABA (gamma-amino-benzoic acid), PEA (phenyl-ethyl-amine), and histamine, and more generally any abnormal alteration of excitatory or inhibitory neurotransmitters that result in a disease state

Common Side Effects Facial flushing or warmth Nausea, stomach discomfort Chest tightness or pressure (usually dose/rate dependent) Headache Fatigue after administration Injection site discomfort, redness, or swelling Mild dizziness Seek Medical Attention For Severe chest pain or difficulty breathing Signs of allergic reaction: hives, facial swelling, throat tightness Fainting or severe dizziness Use in Pregnancy and Breastfeeding The safety of NAD+ therapy during pregnancy and breastfeeding has not been established

In contrast, the local injection of therapeutic drugs increases the local concentration of drugs in the bronchi, reduces lung inflammation, and enhances the therapeutic effect