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and by a grant FPU17/02909 funded by the Spanish Ministry of Universities to E.C.-P

Similarly, a meta-analysis of nine observational studies in older adults found low serum vitamin B 12 concentration to be associated with increased risk for depression, with significant association only in women (100)

(Table 22) Table 22

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Choosing the Right B12 Supplement for Your Needs Selecting an appropriate vitamin B12 supplement requires consideration of several factors, including the reason for supplementation , individual health status, and practical considerations such as cost and availability