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Such an equilibrium in S tail states might be modulated by factors such as oligomerization, palmitoylation, proximity to the Golgi membrane, association with cytosolic proteins, and mutations outside the extended motif 11,69,70

No lethal dose was identified across a wide dose range from 0.006 mg/kg to 20 mg/kg body weight

This involves consulting a clinician and getting relevant labs, typically a serum B12 test

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