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Recent evidence suggests that the autophagy-lysosome pathway is associated with the removal of aggregated polyQ-HTT (Sarkar and Rubinsztein, 2008

miRNAs are small ncRNA molecules, typically 20-30 nucleotides in length, that serve critical roles in structural, enzymatic and regulatory processes across biological systems (58)

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Auto-oxidation of EGCG generates substantial ROS, which may induce apoptosis and inhibit the growth of adipocytes in cancer cells, leading to anticancer and antiobesity properties (Ouyang et al., 2020)

EVs derived from different cell types across various species have been shown to cross the BBB both in vitro and in vivo , delivering cargo such as miRNAs, proteins, and drugs to target cells in the brain [37,42]