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Yes, but always do a patch test first

doi: 10.1126/science.1078540

Multicollinearity issues/too many overlapping covariates : In this work, we start with a large number of covariates (300+) and many covariates overlap i.e

This encompasses mood, wakefulness and sleep, appetite, aggression frequency, circadian rhythms, body temperature, and neuroendocrine activity

Thus, we consider that together with other clinical variables and biomarkers, global MFIS and its domains constitute a diagnostic and prognostic aid in clinical practice for the design of personalized therapeutic strategies