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However, development of CAR-T cells or vaccine therapy as senolityc treatment remain, for the moment, difficult because the permanent activation of these therapies could lead to several side effects and potentially eradicate positive activity of senescence

So-called senolytic drugs, are compounds that are effective both in vitro and in vivo, in targeting and eliminating senescent cells 4

Behavioral assays, including memory-based tasks and spatial navigation tests, are easily adapted to zebrafish models, enabling detailed assessments of cognitive function and neurobehavioral changes

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